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Folate-binding protein (FBP) are proteins that bind folate, typically the folate receptors and reduced folate carrier. It can be a marker for ovarian cancer. It can be measured to help in tumour classification to aid treatment. FBP is over-expressed (20-80 fold) in more than 90% of ovarian and endometrial cancers, as well as 20-50% of breast, lung, colorectal, and renal cell carcinomas. FBP has very limited tissue distribution and expression in non-malignant tissue, making it a good immunotherapy target.〔http://www.marketwatch.com/story/galena-biopharma-to-present-at-the-10th-annual-biotechnology-investor-forum-2011-10-21〕 ==Alternative usage== FBP can refer to protein(s) (e.g. extracted from cow's milk) used to do folic acid assays.〔http://www.scrippslabs.com/enzymes-biochemicals-folate-binding-protein/〕 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Folate-binding protein」の詳細全文を読む スポンサード リンク
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